LOGO DRONET
 Home | Chi siamo | Convegni | News & Comunicazioni | Pubblicazioni | Newsletter | Video Gallery   
informazioni perinformazioni per studenti e giovani informazioni per genitori e insegnantiinformazioni per operatori delle tossicodipendenze
mail to   feed rss

SOSTANZE D'ABUSO
 
RICADUTA E MEMORIA: BASI BIOLOGICHE
BIBLIOGRAFIA
1.Di Chiara G. Role of dopamine in the behavioural actions of nicotine related to addiction. Eur J Pharmacol 2000 Mar 30;393(1-3):295-314
2.Di Chiara G. Drug addiction as dopamine-dependent associative learning disorder.Eur J Pharmacol 1999 Jun 30;375(1-3):13-30
3.Di Chiara G, Tanda G, Bassareo V, Pontieri F, Acquas E, Fenu S, Cadoni C, Carboni E. Drug addiction as a disorder of associative learning. Role of nucleus accumbens shell/extended amygdala dopamine. Ann N Y Acad Sci 1999 Jun 29;877:461-85
4.Bassareo V, Di Chiara G. Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments. Neuroscience 1999 Mar;89(3):637-41
5.Di Chiara G. A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use. J Psychopharmacol 1998;12(1):54-67
6.Garris PA, Kilpatrick M, Bunin MA, Michael D, Walker QD, Wightman RM. Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation. Nature 1999 Mar 4;398(6722):67-9
7.Salamone JD, Cousins MS, Snyder BJ. Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neurosci Biobehav Rev 1997 May;21(3):341-59
8.Ikemoto S, Panksepp J. The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Brain Res Rev 1999 Dec;31(1):6-41
9.Pezze MA, Heidbreder CA, Feldon J, Murphy CA. Selective responding of nucleus accumbens core and shell dopamine to aversively conditioned contextual and discrete stimuli. Neuroscience 2001;108(1):91-102
10.Waelti P, Dickinson A, Schultz W. Dopamine responses comply with basic assumptions of formal learning theory. Nature 2001 Jul 5;412(6842):43-8
11.Robinson TE, Berridge KC. The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction 2000 Aug;95 Suppl 2:S91-117
12.Berridge KC, Robinson TE. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res Brain Res Rev 1998 Dec;28(3):309-69
13.Hyman SE, Malenka RC. Addiction and the brain: the neurobiology of compulsion and its persistence. Nat Rev Neurosci 2001 Oct;2(10):695-703
14.Lyvers M. Drug addiction as a physical disease: the role of physical dependence and other chronic drug-induced neurophysiological changes in compulsive drug self-administration. Exp Clin Psychopharmacol 1998 Feb;6(1):107-25
15.Everitt BJ, Dickinson A, Robbins TW. The neuropsychological basis of addictive behaviour. Brain Res Brain Res Rev 2001 Oct;36(2-3):129-38
16.Koob GF, Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 2001 Feb;24(2):97-129
17.Heyne A, May T, Goll P, Wolffgramm J. Persisting consequences of drug intake: towards a memory of addiction. J Neural Transm 2000;107(6):613-38
18.Berke JD, Hyman SE. Addiction, dopamine, and the molecular mechanisms of memory. Neuron 2000 Mar;25(3):515-32
19.Boening JA. Neurobiology of an addiction memory. J Neural Transm 2001;108(6):755-65
20.Nestler EJ, Barrot M, Self DW. DeltaFosB: a sustained molecular switch for addiction. Proc Natl Acad Sci U S A 2001 Sep 25;98(20):11042-6
21.Freeman WM, Brebner K, Lynch WJ, Patel KM, Robertson DJ, Roberts DC, Vrana KE. Changes in rat frontal cortex gene expression following chronic cocaine. Brain Res Mol Brain Res 2002 Jul 15;104(1):11-20
22.Volkow ND, Fowler JS. Addiction, a disease of compulsion and drive: involvement of the orbitofrontale cortex.Cereb Cortex. 2000 Mar;10(3):318-25.
23.Zhang J, Zhang D, Xu M. Identification of chronic cocaine-induced gene expression through dopamine d1 receptors by using cDNA microarrays. Ann N Y Acad Sci 2002 Jun;965:1-9
24.Sakai N, Thome J, Newton SS, Chen J, Kelz MB, Steffen C, Nestler EJ, Duman RS. Inducible and brain region-specific CREB transgenic mice. Mol Pharmacol 2002 Jun;61(6):1453-64
25.Canales JJ, Capper-Loup C, Hu D, Choe ES, Upadhyay U, Graybiel AM. Shifts in striatal responsivity evoked by chronic stimulation of dopamine and glutamate systems. Brain 2002 Oct;125(Pt 10):2353-2363
26.Zhou Y, Spangler R, Schlussman SD, Yuferov VP, Sora I, Ho A, Uhl GR, Kreek MJ. Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice. Synapse 2002 Sep 15;45(4):220-9
27.Rasmussen DD, Boldt BM, Wilkinson CW, Mitton DR. Chronic daily ethanol and withdrawal: 3. Forebrain pro-opiomelanocortin gene expression and implications for dependence, relapse, and deprivation effect. Alcohol Clin Exp Res 2002 Apr;26(4):535-46
28.Crespo JA, Oliva JM, Ghasemzadeh MB, Kalivas PW, Ambrosio E. Neuroadaptive changes in NMDAR1 gene expression after extinction of cocaine self-administration. Ann N Y Acad Sci 2002 Jun;965:78-91
29.Ujike H, Takaki M, Kodama M, Kuroda S. Gene expression related to synaptogenesis, neuritogenesis, and MAP kinase in behavioral sensitization to psychostimulants. Ann N Y Acad Sci 2002 Jun;965:55-67
30.Nestler EJ. Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci 2001 Feb;2(2):119-28
31.Self DW, Nestler EJ. Relapse to drug-seeking: neural and molecular mechanisms. Drug Alcohol Depend 1998 Jun-Jul;51(1-2):49-60
32.Nestler EJ. Molecular neurobiology of addiction. Am J Addict 2001 Summer;10(3):201-17
33.McFarland K, Kalivas PW.J The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. Neurosci 2001 Nov 1;21(21):8655-63
34.Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, Impey S, Storm DR, Neve RL, Yin JC, Zachariou V, Nestler EJ. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci U S A 2002 Aug 20;99(17):11435-40
35.Mayfield RD, Lewohl JM, Dodd PR, Herlihy A, Liu J, Harris RA.J Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. Neurochem 2002 May;81(4):802-13
36.Bannon MJ, Pruetz B, Manning-Bog AB, Whitty CJ, Michelhaugh SK, Sacchetti P, Granneman JG, Mash DC, Schmidt CJ. Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers. Proc Natl Acad Sci U S A 2002 Apr 30;99(9):6382-5
37.Gardner EL. What we have learned about addiction from animal models of drug self-administration. Proc Natl Acad Sci U S A 2002 Apr 30;99(9):6382-5.
38.Heishman SJ. Behavioral and cognitive effects of smoking: relationship to nicotine addiction. Nicotine Tob Res 1999;1 Suppl 2:S143-7; discussion S165-6.
39.Sinha R. How does stress increase risk of drug abuse and relapse? Psychopharmacology (Berl) 2001 Dec;158(4):343-59
40.Gerra et al., Serotonin transporter gene variants in heroin dependent subjects: relationship with personality traits. Neuropsychiatric genetic, in press
41.Hallikainen T, Saito T, Lachman HM, Volavka J, Pohjalainen T, Ryynanen OP, Kauhanen J, Syvalahti E, Hietala J, Tiihonen J. Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior. Mol Psychiatry 1999 Jul;4(4):385-8.
42.Matsushita et al., Association study of serotonin transporter gene regulatory region polymorphism and alcoholism. 2001 Am J Med Genet
43.Sander T, Harms H, Dufeu P, Kuhn S, Hoehe M, Lesch KP, Rommelspacher H, Schmidt LG. Serotonin transporter gene variants in alcohol-dependent subjects with dissocial personality disorder. Biol Psychiatry 1998 Jun 15;43(12):908-12
44.Buydens-Branchey L, Branchey M, Fergeson P, Hudson J, McKernin C. The meta-chlorophenylpiperazine challenge test in cocaine addicts: hormonal and psychological responses. Biol Psychiatry 1997 Jun 1;41(11):1071-86
45.Coccaro EF, Siever LJ, Klar HM, Maurer G, Cochrane K, Cooper TB, Mohs RC, Davis KL. Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior. Arch Gen Psychiatry 1989 Jul;46(7):587-99 Erratum in: Arch Gen Psychiatry 1990 Feb;47(2):124
46.Gerra G., Fertonani G., Zaimovic A., Rota-Graziosi I., Avanzini P., Caccavari R., Delsignore R. and Lucchini A. Hostility in heroin abusers subtypes: fluoxetine and naltrexone treatment. Progress in Neuropsychopharmacology and Biological Psychiatry, 19: 1225-1237,1995
47.Gerra G., Ferri M., Zaimovic A., Giucastro G., Palladino M., Sartori R., Delsignore R., Maestri D., Marzocchi G., Brambilla F. Gabaergic function in detoxified heroin addicts: relationship to anxiety disorders. Psychiatry Research, 77:89-96, 1998
48.Tiihonen J, Kuikka J, Bergstrom K, Hakola P, Karhu J, Ryynanen OP, Fohr J. Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. Nat Med 1995 Jul;1(7):654-7
49.Gerra G., Zaimovic A., Timpano M., Zambelli U., Begarani M., Marzocchi G.F., Ferri M., Delsignore R., Brambilla F., Neuroendocrine correlates of temperament traits in abstinent opiate addicts. Journal of Substance Abuse, 11:337-354, 2000.
50.Young et al., 2002. Dopamine transporter polymorphism associated with externalizing behavior problems in children. Am J Med Genet
51.Gerra G., Zaimovic A., Moi G., Delsignore R.*, Caccavari R., Brambilla F. Neuroendocrine correlates of antisocial personality disorder in abstinent heroin dependent subjects. Addiction Biology, in press
52.Sipe JC, Chiang K, Gerber AL, Beutler E, Cravatt BF. A missense mutation in human fatty acid amide hydrolase associated with problem drug use. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8394-9.
53.Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9608-13.
54.Gerra G., Caccavari R., Fontanesi B., Delsignore R., Fertonani AG., Marcato A., Maestri D, Avanzini P., Perna G., Brambilla F. Alpha-2-adrenoreceptors sensitivity in heroin addicts with and without previous attention deficit disorder/ hyperactivity and conduct disorder. Neuropsychobiology , 30: 15-19, 1994.
55.Gill M, Daly G, Heron S, Hawi Z, Fitzgerald M. Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism. Mol Psychiatry 1997 Jul;2(4):311-3
Primo Piano

Dipartimento Politiche Antidroga
Presidenza del Consiglio dei Ministri

- Prevention Strategy and Policy Makers (IT, EN, FRA, ESP, ARAB, RUS)
- Principi generali della posizione italiana contro l’uso di droghe (IT, EN)
- Accordo di collaborazione scientifica Italia-USA (IT, EN)
- Dichiarazione DPA collaborazioni scientifiche internazionali (IT, EN)

banner Progetto Comuni Italia

 

Vocabolari
VOCABOLARI

- Alcohol and drug terms - WHO
- Terminology & information - UNODC

 


Oggi i giornali parlano di droga





Home | FAQ's | Site Map | Credits | Help | Informativa sull'utiizzo dei cookie | RSS feed rss
N N D Network Nazionale sulle Dipendenze